Founded by a doctor and a team of patient safety experts, Dosium has a clear mission: to reduce avoidable harm from prescribing errors - a widespread yet preventable issue. Medication errors are responsible for over 1,700 preventable deaths in the UK each year - a figure on par with annual road traffic fatalities - so the issue is vital to get under control.
At the heart of Dosium’s approach is Touchdose, a decision support tool that provides indication-based, patient-specific dosing recommendations directly into clinicians’ hands. It integrates with Electronic Health Records (EHR) and Electronic Prescribing and Medication Administration (EPMA) systems, and draws from the British National Formulary (BNF) and BNF for Children (BNFC).
Touchdose automatically calculates the right dose for any drug, patient, and indication - including frequency, duration, and route of administration - while incorporating local guidelines in real time. It offers a safer alternative to manual calculations and unregulated apps, and avoids the pitfalls of current systems, many of which rely on excessive alerts.
In real-world use, Touchdose has shown significant impact.
At St Mary’s Hospital, paediatric clinicians using the tool were 83% less likely to make a prescribing error, with error rates dropping from 7.1% to just 1.2%.
Dosium originated at Imperial College London’s Institute of Global Health Innovation, bringing together expertise from trauma, critical care, and frontline practice to design technology that genuinely enhances prescribing safety.
Leadership Team
Dosium’s leadership team is made up of clinicians, academics and engineers dedicated to improving patient outcomes and save lives.
Nicholas Applebaum
CEO and Co-Founder
A medication safety expert with roots in frontline surgery, Nick is driven by the urgent need to tackle life-threatening drug errors. After completing his PhD at Imperial College London, he partnered with Lord Ara Darzi, examining how clinical decisions are made under pressure. A Member of the Royal College of Surgeons, Fellow of the British Computer Society, and Honorary Research Fellow at Imperial’s Institute of Global Health Innovation, Nick has dedicated his career to pushing the boundaries of patient safety.
John Morrell
CTO & Co-Founder
An experienced full-stack developer, John has led Dosium’s software development team since 2017, including data modelling, BNF data translation, APIs and cloud services. He has a particular interest in test-driven development, automation and continuous integration / quality assurance. With extensive experience in delivering secure, high-profile applications, including the mobile launch of BBC iPlayer, John brings a wealth of expertise in building safe and scalable solutions.
Calandra Feather
Clinical Safety Officer
Calandra is a registered Paediatric Nurse who specialised in Paediatric Intensive Care before moving into clinical academic research. She completed her PhD at Imperial College London, focusing on prescribing practices, indication documentation, and the evaluation of Dosium’s Touchdose solution. Calandra is also an Honorary Health Services Researcher at the Centre for Medication Safety and Service Quality at Imperial College Healthcare NHS Trust and an Honorary Clinical Research Fellow at Imperial College London.
Marius-Octavian Matei
Senior Software Engineer
Marius delivers technical integration of Touchdose for our trust partners. He is a highly skilled engineer and technical architect with over a decade of experience. In recent years, he has specialised in developing healthcare integration solutions, primarily using HL7 FHIR and SMART on FHIR standards, and improving data interoperability with coding systems like UCUM, SNOMED, dm+d, LOINC, and RxNorm.
Elliott Gordon
Product Manager and Engineer
With his background in mechatronics engineering, Elliott is an integral part of Dosium's product team. He works closely with trust clinical teams, ensuring that Touchdose is configured to their needs. Elliott acts as the bridge between the technical team and clinical requirements, taking user feedback and data analytics to improve the experience of Touchdose's users.